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令和3年〜7年度 学術変革領域研究A
生物を凌駕する
無細胞分子システムのボトムアップ構築学

研究成果一覧

原著論文

  1. Cell-Free Biosensors Based on Modular Eukaryotic Riboswitches That Function in One Pot at Ambient Temperature
    Atsushi Ogawa, Masahiro Fujikawa, Kazuki Onishi and Hajime Takahashi
    ACS Synth. Biol. 2024, 13, 7, 2238–2245

  2. Reconstitution of Myoglobin with Iron Porphycene Generates an Artificial Aldoxime Dehydratase with Expanded Catalytic Activities
    Shunsuke Kato, Miteki Abe, Harald Gröger and Takashi Hayashi
    ACS Catal. 2024, ASAP.

  3. Characterization and regulation of 2D-3D convertible lipid membrane transformation
    Wancheng Zhang, Yuta Uei, Tomoaki Matsuura and Atsushi Maruyama
    Biomater. Sci., 2024, in press.

  4. Switchable and orthogonal gene expression control inside artificial cells by synthetic riboswitches
    Yuta Ishii, Keisuke Fukunaga, Aileen Cooney, Yohei Yokobayashi and Tomoaki Matsuura
    Chem. Commun., 2024, in press.
  5. Slow freeze-thaw cycles enhanced hybridization of kilobase DNA with long complementary sticky ends
    Natsumi Noda, Kohei Nomura, Naho Takahashi, Fumitaka Hashiya, Hiroshi Abe and Tomoaki Matsuura
    ChemSystemsChem, 2024, in press.

  6. Configurational Changes of Retinal Schiff Base during Membrane Na+ Transport by a Sodium Pumping Rhodopsin
    Tomotsumi Fujisawa, Kouta Kinoue, Ryouhei Seike, Takashi Kikukawa and Masashi Unno
    J. Phys. Chem. Lett., 2024, 15, 7, 1993–1998

  7. Effective design of PEGylated polyion complex (PIC) nanoparticles for enhancing PIC internalisation in cells utilising block copolymer combinations with mismatched ionic chain lengths
    Fadlina Aulia, Hiroaki Matsuba, Shoya Adachi, Takumi Yamada, Ikuhiko Nakase, Teruki Nii, Takeshi Mori, Yoshiki Katayama and Akihiro Kishimura
    J. Mater. Chem. B, 2024, in press.

  8. Preparation of cellular membrane-mimicking glycopolymer interfaces by the solvent-assisted method on QCM-D sensor chips and their molecular recognition
    Masanori Nagao, Tsukuru Masuda, Madoka Takai and Yoshiko Miura
    J. Mater. Chem. B, 2024, in press.

  9. Lipid vesicle-based molecular robots
    Zugui Peng, Shoji Iwabuchi, Kayano Izumi, Sotaro Takiguchi, Misa Yamaji, Shoko Fujita, Harune Suzuki, Fumika Kambara, Genki Fukasawa, Aileen Cooney, Lorenzo Di Michele, Yuval Elani, Tomoaki Matsuura and Ryuji Kawano
    Lab Chip, 2024、in press.

  10. Evolution of hierarchy and irreversibility in theoretical cell differentiation model
    Yoshiyuki T Nakamura, Yusuke Himeoka, Nen Saito, Chikara Furusawa
    PNAS Nexus, 2024, 3(1), pgad454

  11. Real-time monitoring of the amyloid β1–42 monomer-to-oligomer channel transition using a lipid bilayer system
    Yuri Numaguchi, Kaori Tsukakoshi, Nanami Takeuchi, Yuki Suzuki, Kazunori Ikebukuro, Ryuji Kawano
    PNAS Nexus, 2024, 3(1), pgad437

  12. Multimolecular Competition Effect as a Modulator of Protein Localization and Biochemical Networks in Cell-Size Space
    Saki Nishikawa, Gaku Sato, Sakura Takada, Shunshi Kohyama, Gen Honda, Miho Yanagisawa, Yutaka Hori, Nobuhide Doi, Natsuhiko Yoshinaga, Kei Fujiwara
    Adv. Sci., 2023, e2308030.

  13. Multistep conformational changes leading to the gate opening of light-driven sodium pump rhodopsin
    Yukino Sato, Tsubasa Hashimoto, Koji Kat, Akiko Okamura, Kaito Hasegawa, Tsukasa Shinone, Yoshikazu Tanaka, Yoshiki Tanaka, Tomoya Tsukazaki, Takashi Tsukamoto, Makoto Demura, Min Yao, Takashi Kikukawa
    J. Biol. Chem., 2023, 299(12).

  14. Correlation between Self-Folding Behavior of Amphiphilic Polymers and Their Molecular Flexibility
    Masanori Nagao and Yoshiko Miura
    ACS Macro Lett., 2023, 12, 6, 733-737.

  15. Engineering metabolic cycle-inspired hydrogels with enzyme-fueled programmable transient volume changes
    Young Kyoung Hong, Masahiko Nakamoto and Michiya Matsusaki
    J. Mater. Chem. B, 2023, 11, 8136-8141.

  16. Elastic Polymer Coated Nanoparticles with Fast Clearance for 19F MR Imaging
    Yuki Konishi, Masafumi Minoshima, Kohei Fujihara, Takayuki Uchihashi, Kazuya Kikuchi
    Angew. Chem. Int. Ed., 2023, 1433-7851.

  17. Iron azaphthalocyanine electrocatalysts for enhancing oxygen reduction reactions under neutral conditions and power density in microbial fuel cells
    Edwin Osebe Nyangau, Hiroya Abe, Yuta Nakayasu, Masaki Umetsu, Masaru Watanabe, Chika Tada
    Bioresource Technology Reports, 2023, 101565.

  18. Structural requirements of a glycolipid MPIase for membrane protein integration
    Kohki Fujikawa, Youjung Han, Tsukiho Osawa, Shoko Mori, Kaoru Nomura, Maki Muramoto, Ken-ichi Nishiyama, Keiko Shimamoto
    Chem. Eur. J., 2023, 29(30), e202300437.

  19. Chitin- and Streptavidin-Mediated Affinity Purification Systems: A Screening Platform for Enzyme Discovery
    Shunsuke Kato, Koki Takeuchi, Motonao Iwaki, Kentaro Miyazaki, Kohsuke Honda, Takashi Hayashi
    Angew. Chem. Int. Ed., 2023, e202303764.

  20. Nanofluidic Aptamer Nanoarray to Enable Stochastic Capture of Single Proteins at Normal Concentrations
    Jinbin Yang, Hiroki Kamai, Yong Wang, Yan Xu
    Small, 2023, 2301013.

  21. A simple chemical method to nondestructively regenerate functional nanochannels for single-molecule studies
    Jinbin Yang, Hiroki Kamai and Yan Xu
    Sensors and Actuators B: Chemical, 2023, 134106.

  22. Mussel-inspired interfacial ultrathin films for cellular adhesion on the wrinkled surfaces of hydrophobic fluids
    Hiroya Abe, Tomoya Ina, Hirokazu Kaji and Matsuhiko Nishizawa
    Polymer Journal, 2023, 1-6.

  23. Nanopore Filter: A Method for Counting and Extracting Single DNA Molecules Using a Biological Nanopore
    Asuka Tada, Nanami Takeuchi, Kan Shoji, and Ryuji Kawano
    Anal. Chem., 2023, ASAP.

  24. Investigation of Compatibility between DNA Replication, Transcription, and Translation for in Vitro Central Dogma
    Kaito Seo and Norikazu Ichihashi
    ACS Synth. Biol., 2023, 12, 6, 1813-1822.

  25. Self-assembled GA-Repeated Peptides as a Biomolecular Scaffold for Biosensing with MoS2 Electrochemical Transistors
    Hironaga Noguchi, Yoshiki Nakamura, Sayaka Tezuka, Takakazu Seki, Kazuki Yatsu, Takuma Narimatsu, Yasuaki Nakata, and Yuhei Hayamizu
    ACS Appl. Mater. Interfaces, 2023, 15, 11, 14058–14066.

  26. Dynamic frustrated charge hotspots created by charge density modulation sequester globular proteins into complex coacervates
    Biplab K C, Teruki Nii, Takeshi Mori, Yoshiki Katayama, Akihiro Kishimura
    Chem. Sci., 2023, 14, 6608-6620.

  27. Spatiotemporal Control of Ice Crystallization in Supercooled Water via an Ultrashort Laser Impulse
    Hozumi Takahashi, Tatsuya Kono, Kosuke Sawada, Satoru Kumano, Yuka Tsuri, Mihoko Maruyama, Masashi Yoshimura, Daisuke Takahashi, Yukio Kawamura, Matsuo Uemura, Seiichiro Nakabayashi, Yusuke Mori, Yoichiroh Hosokawa, and Hiroshi Y. Yoshikawa
    J. Phys. Chem. Lett., 2023, 14, 19, 4394–4402.

  28. Flexible Glass-Based Hybrid Nanofluidic Device to Enable the Active Regulation of Single-Molecule Flows
    Hiroto Kawagishi, Shun-ichi Funano, Yo Tanaka, and Yan Xu
    Nano Lett., 2023, 23, 6, 2210-2218.

  29. Phenylazothiazoles as Visible-Light Photoswitches
    Runze Lin, P. K. Hashim, Saugata Sahu, Ammathnadu S. Amrutha, Nusaiba Madappuram Cheruthu, Shakkeeb Thazhathethil, Kiyonori Takahashi, Takayoshi Nakamura, Takashi Kikukawa, and Nobuyuki Tamaoki
    J. Am. Chem. Soc., 2023, 145, 16, 9072-9080.

  30. Foci-forming regions of pyruvate kinase and enolase at the molecular surface incorporate proteins into yeast cytoplasmic metabolic enzymes transiently assembling (META) bodies
    Ryotaro Utsumi, Yuki Murata, Sayoko Ito-Harashima, Misaki Akai, Natsuko Miura, Kouichi Kuroda, Mitsuyoshi Ueda, Michihiko Kataoka
    Plos one, 2023, in press.

  31. In Vitro Transcription/Translation-Coupled DNA Replication through Partial Regeneration of 20 Aminoacyl-tRNA Synthetases
    Katsumi Hagino, Norikazu Ichihashi
    ACS Synth. Biol., 2023, 12, 4, 1252-1263.

  32. Increased Enzyme Loading in PICsomes via Controlling Membrane Permeability Improves Enzyme Prodrug Cancer Therapy Outcome
    Akinori Goto, Yasutaka Anraku, Shigeto Fukushima, Akihiro Kishimura
    Polymers, 2023, 15, 1368.

  33. Characterization of retinal chromophore and protonated Schiff base in Thermoplasmatales archaeon heliorhodopsin using solid-state NMR spectroscopy
    Shibuki Suzuki, Sari Kumagai, Toshio Nagashima, Toshio Yamazaki, Takashi Okitsu, Akimori Wada, Akira Naito, Kota Katayama, Keiichi Inoue, Hideki Kandori, Izuru Kawamura
    Biophys. Chem., 2023, 296, 106991.

  34. Evolutionary Engineering of a Cp*Rh(III) Complex-Linked Artificial Metalloenzyme with a Chimeric β-Barrel Protein Scaffold
    Shunsuke Kato, Akira Onoda, Ulrich Schwaneberg, Takashi Hayashi
    J. Am. Chem. Soc., 2023, in press.

  35. Development of a Versatile Protein Labeling Tool for Live-Cell Imaging Using Fluorescent ß-Lactamase Inhibitors
    Masafumi Minoshima, Taro Umeno, Kohei Kadooka, Margaux Roux, Namiko Yamada, Kazuya Kikuchi
    Angew. Chem. Int. Ed., 2023, in press.

  36. Toward nanofluidics-based mass spectrometry for exploring the unknown complex and heterogeneous subcellular worlds
    Nattapong Chantipmanee, Yan Xu
    VIEW, 2023, 4, 1, 20220036
    本誌表紙に採択されました

  37. Cell-free expression of de novo designed peptides that form β-barrel nanopores
    Shoko Fujita, Izuru Kawamura, Ryuji Kawano
    ACS Nano, 2023, 17, 4, 3358.

  38. Liposome Deformation Induced by Membrane-Binding Peptides
    Kayano Izumi, Chihiro Saito, Ryuji Kawano
    Micromachines, 2023, 14, 373.

  39. Facile preparation of hexagonal nanosheets via polyion complex formation from α-helical polypeptides and polyphosphate-based molecules
    Asmariah Ahmad, Tomoki Maruyama, Teruki Nii, Takeshi Mori, Yoshiki Katayama. Akihiro Kishimura
    Chem comm., 2023, 59, 1657–1660.

  40. Designable peptides on graphene field-effect transistors for selective detection of odor molecules
    Chishu Homma, Mirano Tsukiiwa, Hironaga Noguchi, Masayoshi Tanaka, Mina Okochi, Hideyuki Tomizawa, Yoshiaki Sugizaki, Atsunobu Isobayashi, Yuhei Hayamizu
    Biosens. Bioelectron., 2023, 224, 115047.

  41. Emergence of growth and dormancy from a kinetic model of the Escherichia coli central carbon metabolism
    Yusuke Himeoka and Namiko Mitarai
    Phys. Rev. Research, 2022, 4, 043223.

  42. Surfactant-Assisted Purification of Hydrophobic DNA Nanostructures
    Shoji Iwabuchi, Shin-ichiro M. Nomura, Yusuke Sato
    ChemBioChem, 2022, e202200.

  43. ePURE_JSBML: A tool for constructing a deterministic model of a reconstituted Escherichia coli protein translation system with a user-specified nucleic acid sequence
    Yoshihiro Shimizu, Naoki Tanimura, Tomoaki Matsuura
    Adv. Biology, 2022, 2200177.

  44. Plausible pathway for a host-parasite molecular replication network to increase its complexity through Darwinian evolution
    Rikuto Kamiura,Ryo Mizuuchi,Norikazu Ichihashi
    PLoS Comput. Biol.,2022, 1010709.

  45. Fabrication of a polymeric inhibitor of proximal metabolic enzymes in hypoxia for synergistic Inhibition of cancer cell proliferation, survival, and migration
    Yuki Koba, Masahiko Nakamoto, Michiya Matsusaki
    ACS Appl. Mater. Interfaces, 2022, 14, 46, 51790−51797.

  46. A peptide nanocage constructed by self-assembly of oligoproline conjugates
    Shogo Matsubara, Yui Okamoto, Masaru Yoshikawa, Shinya Tsukiji, Masahiro Higuchi
    Bioconj. Chem., 2022, 33, 10, 1785-1788.

  47. A methodology for creating thermostabilized mutants of G-protein coupled receptors by combining statistical thermodynamics and evolutionary molecular engineering
    Kanna Sugaya, Satoshi Yasuda, Shingo Sato, Chen Sisi, Taisei Yamamoto, Daisuke Umeno, Tomoaki Matsuura, Tomohiko Hayashi, Satoshi Ogasawara, Masahiro Kinoshita, Takeshi Murata
    Protein Sci., 2022, 31, 9, e4404.

  48. Three-dimensional structure of the antimicrobial peptide cecropin P1 in dodecylphosphocholine micelles and the role of the C-terminal residues
    Hao Gu, Takasumi Kato, Hiroyuki Kumeta, Yasuhiro Kumaki, Takashi Tsukamoto, Takashi Kikukawa, Makoto Demura, Hiroaki Ishida, Hans J. Vogel, Tomoyasu Aizawa
    ACS Omega, 2022, 7, 36, 31924−31934.

  49. Protein-structure-dependent spectral shifts of near-infrared photoluminescence from locally functionalized single-walled carbon nanotubes based on avidin–biotin interactions
    Yoshiaki Niidome, Rie Wakabayashi, Masahiro Goto, Tsuyohiko Fujigaya, Tomohiro Shiraki
    Nanoscale, 2022, 14, 13090–13097.

  50. Molecular crowding elicits the acceleration of enzymatic crosslinking of macromolecular substrates
    Ryo Sato, Kosuke Minamihata, Rie Wakabayashi, Masahiro Goto, Noriho Kamiya
    Org. Biomol. Chem., 2022, 21, 306–314.

  51. Effects of pulse duration on laser-induced crystallization of urea from 300 to 1200 fs: impact of cavitation bubbles on crystal nucleation
    Yuka Tsuri, Mihoko Maruyama, Katsuo Tsukamoto, Hiroaki Adachi, Kazufumi Takano, Shigeyoshi Usami, Masayuki Imanishi, Masashi Yoshimura, Hiroshi Y. Yoshikawa, Yusuke Mori
    Appl. Phys. A, 2022, 128, 803.

  52. Synthesis of well-defined cyclic glycopolymers and the relationship between their physical properties and their interaction with lectins
    Masanori Nagao, Yu Hoshino, Yoshiko Miura
    Polym. Chem., 2022, 13, 5453–5457.

  53. Mechanical guidance of self-condensation patterns of differentiating progeny
    Takahisa Matsuzaki, Yuko Shimokawa, Hiroyuki Koike, Masaki Kimura, Yuma Kawano, Nao Okuma, Ryuzo Kawamura, Yosuke Yoneyama, Yasuro Furuichi, Fumihiko Hakuno, Shin-Ichiro Takahashi, Seiichiro Nakabayashi, Satoshi Okamoto, Hiromitsu Nakauchi, Hideki Taniguchi, Takanori Takebe, Hiroshi Y. Yoshikawa
    iScience, 2022, 25, 10, 105109.

  54. Practice of responsible research and innovation in the formulation and revision of ethical principles of molecular robotics in Japan
    Ken Komiya, Ryuma Shineha, Naoto Kawahara
    SN Appl. Sci., 2022, 4, 305.

  55. Experimental evidence for the correlation between RNA structural fluctuations and the frequency of beneficial mutations
    Yutaro Maeda, Ryo Mizuuchi, Shuji Shigenobu, Atsushi Shibai, Hazuki Kotani, Chikara Furusawa, Norikazu Ichihashi
    RNA, 2022, 28, 12, 1659-1667.

  56. Controlling the periodicity of a reaction–diffusion wave in artificial cells by a two-way energy supplier
    Sakura Takada, Natsuhiko Yoshinaga, Nobuhide Doi, Kei Fujiwara
    ACS Nano, 2022, 16, 10, 16853−16861.

  57. Mutations conferring SO42− pumping ability on the cyanobacterial anion pump rhodopsin and the resultant unique features of the mutant
    Yuhei Doi, Jo Watanabe, Ryota Nii, Takashi Tsukamoto, Makoto Demura, Yuki Sudo, Takashi Kikukawa
    Sci. Rep., 2022, 12, 16422.

  58. A chemogenetic platform for controlling plasma membrane signaling and synthetic signal oscillation
    Sachio Suzuki, Akinobu Nakamura, Yuka Hatano, Masaru Yoshikawa, Tatsuyuki Yoshii, Shunsuke Sawada, Kyoko Atsuta-Tsunoda, Kazuhiro Aoki, Shinya Tsukiji
    Cell Chem. Biol., 2022, 29, 9, 1446-1464.e10.

  59. Reisomerization of retinal represents a molecular switch mediating Na+ uptake and release by a bacterial sodium-pumping rhodopsin
    Tomotsumi Fujisawa, Kouta Kinoue, Ryouhei Seike, Takashi Kikukawa, Masashi Unno
    J. Biol. Chem., 2022, 298, 9, 102366.

  60. Biomacromolecule-fueled transient volume phase transition of a hydrogel
    Masahiko Nakamoto, Shiro Kitano, Michiya Matsusaki
    Angew. Chem. Int. Ed., 2022, 61, 33,e202205125.

  61. Role of a bacterial glycolipid in Sec-independent membrane protein insertion
    Kaoru Nomura, Shoko Mori, Kohki Fujikawa, Tsukiho Osawa, Shugo Tsuda, Kumiko Yoshizawa-Kumagaye, Shun Masuda, Hideki Nishio, Taku Yoshiya, Takao Yoda, Masafumi Shionyu, Tsuyoshi Shirai, Ken-ichi Nishiyama, Keiko Shimamoto
    Sci. Rep., 2022, 12, 12231.

  62. Transfer RNA synthesis-coupled translation and DNA replication in a reconstituted transcription/translation system
    Ryota Miyachi, Yoshihiro Shimizu, Norikazu Ichihashi
    ACS Synth. Biol., 2022, 11 , 8,2791-2799.

  63. One-step preparation of cell-free ATP regeneration module based on non-oxidative glycolysis using thermophilic enzymes
    Gladwin Suryatin Alim, Kenji Okano, Kohsuke Honda
    ChemBioChem, 2022, 23, 16,e202200210.

  64. Pattern recognition of microRNA expression in body fluids using nanopore decoding at subfemtomolar concentrations
    Nanami Takeuchi, Moe Hiratani, Ryuji Kawano
    JACS Au, 2022, 2, 9, 1829–1838.
    プレスリリース:ナノポアを用いた血中がんマーカーのパターン識別に成功!―DNAコンピューティング技術による並列計算を利用―, 東京農工大学
    メディア報道:日本経済新聞, EurekAlert!, Bioengineer.org, SCIENMAG, TECH+, GEN, ecancer, Jano.es, eBiotrade, List23, tetracyclined7k, AZoLifeSciences

  65. A photoactivatable self-localizing ligand with improved photosensitivity for chemo-optogenetic control of protein localization in living cells
    Tatsuyuki Yoshii, Choji Oki, Shinya Tsukiji
    Bioorg. Med. Chem. Lett., 2022, 72, 128865.

  66. A protocol to construct RNA-protein devices for photochemical translational regulation of synthetic mRNAs in mammalian cells
    Hideyuki Nakanishi, Tatsuyuki Yoshii, Shinya Tsukiji, Hirohide Saito
    STAR Protoc., 2022, 101451.

  67. One-step preparation of cell-free ATP regeneration module based on non-oxidative glycolysis using thermophilic enzymes
    Gladwin Suryatin Alim, Kenji Okano, Kohsuke Honda
    ChemBioChem,, 2022, e202200210.

  68. Fluorescent hydrogel based on self-assembling acridonylalanine-phenylalanine
    Yuzuha Araki, Hiroki Shirakata, Tetsuya Nakagawa, Takashi Ubukata, Yasushi Yokoyama, Izuru Kawamurabr
    Chem. Lett., 2022, 51, 7, 687–689.

  69. Functionalized silicone elastomer via alkaline solution to coat phosphorylcholine-based copolymer containing organosilane to improve hemocompatibility for medical devices
    Fang-Yu Chou, Shintaro Hara, Kazuto Uchida, Youichi Matsuo, Tsukuru Masuda, Ryo Yokoi, Toshiya Ono, Masaki Anraku, Takashi Isoyama, Madoka Takai
    Front. Mater., 2022, 9, 877755.

  70. Construction of a reduction-responsive DNA microsphere using a reduction-cleavable spacer based on a nitrobenzene scaffold
    Sayuri L. Higashi, Ayaka Isogami, Junko Takahashi, Aya Shibata, Koichiro M. Hirosawa, Kenichi G.N. Suzuki, Shunsuke Sawada, Shinya Tsukiji, Kazunori Matsuura, Masato Ikeda
    Chem. Eur. J., 2022, 17, 10, e202200142.

  71. Photoreaction pathways of bacteriorhodopsin and its D96N mutant as revealed by in-situ photoirradiation solid-state NMR
    Arisu Shigeta, Yuto Otani, Ryota Miyasa, Yoshiteru Makino, Izuru Kawamura, Takashi Okitsu, Akimori Wada, Akira Naito
    Membranes, 2022, 12, 3, 279.

  72. Silver-loaded carboxymethyl cellulose nonwoven sheet with controlled counterions for infected wound healing
    Seiichi Ohta, Kento Mitsuhashi, Arvind K. Singh Chandel, Pan Qi, Noriko Nakamura, Akiko Nakamichi, Hiromi Yoshida, Gento Yamaguchi, Yuichi Hara, Ryo Sasaki, Masaya Fuke, Madoka Takai, Taichi Ito
    Carbohydr. Polym., 2022, 286, 119289.

  73. Cell-free synthesis of human endothelin receptors and its application to ribosome display
    Hiroki Nakai, Kinuka Isshiki, Masato Hattori, Hiromasa Maehira, Tatsumi Yamaguchi, Keiko Masuda, Yoshihiro Shimizu, Takayoshi Watanabe, Takahiro Hohsaka, Wataru Shihoya, Osamu Nureki, Yasuhiko Kato, Hajime Watanabe, and Tomoaki Matsuura
    Anal. Chem., 2022, 94, 9, 3831–3839.

  74. Functional visualization of NK cell-mediated killing of metastatic single tumor cells
    Hiroshi Ichise, Shoko Tsukamoto, Tsuyoshi Hirashima, Yoshinobu Konishi, Choji Oki, Shinya Tsukiji, Satoshi Iwano, Atsushi Miyawaki, Kenta Sumiyama, Kenta Terai, Michiyuki Matsuda
    eLife, 2022, 11, e76269.

  75. Review “Recent progress and perspectives in applications of 2-methacryloyloxyethyl phosphorylcholine polymers in biodevices at small scales
    Sasikarn Seetasang, Yan Xu
    J. Mater. Chem. B,2022, 10, 14, 2323–2337.

  76. Review “Condensate Formation by Metabolic Enzymes in Saccharomyces cerevisiae
    Natsuko Miura
    Microorganisms, 2022, 10, 2, 232.

  77. A biomimetic anti-biofouling coating in nanofluidic channels
    Sumire Fukuda, Yan Xu
    J. Mater. Chem. B, 2022, 10, 14, 2481–2489.
    Journal of Materials Chemistry B HOT Papersに選出された

  78. Chimeric mutants of staphylococcal hemolysin, which actas both one-component and two-component hemolysin, created by grafting the stem domain
    Nouran Ghanem, Natsuki Kanagami, Takashi Matsui, Kein Takeda, Jun Kaneko, Yasuyuki Shiraishi, Christian A. Choe, Tomomi Uchikubo-Kamo, Mikako Shirouzu, Tsubasa Hashimoto, Tomohisa Ogawa, Tomoaki Matsuura, Po-Ssu Huang, Takeshi Yokoyama, Yoshikazu Tanaka
    FEBS J., 2022, 289, 12, 3505–3520.

  79. Review “Design of biointerfaces composed of soft materials using controlled radical polymerization
    Tsukuru Masuda, Madoka Takai
    J. Mater. Chem. B, 2022, 10, 10, 1473–1485.

  80. Photoswitching of 5-phenylazopyrimidines in crystalline powders and thin films
    Eliška Procházková, Juraj Filo, Lucie Mužíková Čechová, Martin Dračínský, Ivana Císařová, Zlatko Janeba, Izuru Kawamura, Akira Naito, Peter Nádaždy, Peter Šiffalovič, Marek Cigáň
    Dyes Pigm., 2022, 199, 110066.

  81. Cell adhesion and migration on thickness gradient bilayer polymer brush surfaces: effects of properties of polymeric materials of the underlayer
    Zahra Afzali, Taishi Matsushita, Akinori Kogure, Tsukuru Masuda, Tomoyuki Azuma, Keiichiro Kushiro, Toshihiro Kasama, Ryo Miyake, Madoka Takai
    ACS Appl. Mater. Interfaces, 2022, 14, 2, 2605–2617.

  82. Review “Recent advances in research on biointerfaces: From cell surfaces to artificial interfaces
    Katsutoshi Hori, Shogo Yoshimoto, Tomoko Yoshino, Tamotsu Zako, Gen Hirao, Satoshi Fujita, Chikashi Nakamura, Ayana Yamagishi, Noriho Kamiya
    J. Biosci. Bioeng., 2022, 133, 3, 195–207.

  83. Two-dimensional imaging of a model pharmaceutical dosage tablet using a scanning vibrational circular dichroism system
    Hisako Sato, Sumio Aisawa, Honoka Ida, Masaru Shimizu, Keisuke Watanabe, Jun Koshobu, Jun Yoshida, Izuru Kawamura
    Chem. Lett., 2022, 51, 2, 205-207.

  84. Nanofluidics for sub-single cellular studies: Nascent progress, critical technologies, and future perspectives
    Jinbin Yang, Yan Xu
    Chin. Chem. Lett., 2022, 33, 6, 2799.

  85. De novo design of a nanopore for single molecule detection that incorporates a β-hairpin peptide
    Keisuke Shimizu, Batsaikhan Mijiddorj, Masataka Usami, Ikuro Mizoguchi, Shuhei Yoshida, Shiori Akayama, Yoshio Hamada, Akifumi Ohyama, Kenji Usui, Izuru Kawamura, Ryuji Kawano
    Nature Nanotechnol., 2022, 17, 67.

  86. Identification of conditions for efficient cell-sized liposome preparation using commercially available reconstituted in vitro transcription-translation system
    Atsuko Uyeda, Sabrina Galiñanes Reyes, Takashi Kanamori, Tomoaki Matsuura
    J. Biosci. Bioeng., 2022, 133, 2, 181.

  87. A Dual Promoter System to Monitor IFN-γ Signaling in vivo at Single-cell Resolution
    Taisei Tanaka, Yoshinobu Konishi, Hiroshi Ichise, Shinya Tsukiji, Michiyuki Matsuda, Kenta Terai
    Cell Struct. Funct., 2022, 46, 2, 103

  88. pH-responsive water-soluble polymer carriers for cell-selective metabolic sialylation labeling
    Tingbi Zhao, Tsukuru Masuda, Madoka Takai
    Anal. Chem., 2021, 93, 46, 15420.

  89. Viewpoint “ Modularly built synthetic membraneless organelles enabling targeted protein sequestration and release
    Shuhao Lin, Daiki Hirayama, Gembu Maryu, Kimiya Matsuda, Naoya Hino, Eriko Deguchi, Kazuhiro Masaru Yoshikawa, Shinya Tsukiji
    Biochemistry, 2021, 60, 44, 3273.

  90. Redundant roles of EGFR ligands in the ERK activation waves during collective cell migration
    Shuhao Lin, Daiki Hirayama, Gembu Maryu, Kimiya Matsuda, Naoya Hino, Eriko Deguchi, Kazuhiro Aoki, Ryo Iwamoto, Kenta Terai, Michiyuki Matsuda
    Life Sci. Alliance, 2021, 5, e202101206.

  91. Fabrication of nanoscale gas–liquid interfaces in hydrophilic/hydrophobic nanopatterned nanofluidic channels
    Hiroto Kawagishi, Shuichi Kawamata, Yan Xu
    Nano Lett., 2021, 21, 24, 10555.
    掲載号(2021年21巻24号)の表紙に採択
    プレスリリース:ナノスケールで物質の濃縮効果を発見―ナノ流体デバイスによる超微小気液界面の作製と効果―, 大阪府立大学・JST
    メディア報道:日刊工業新聞, EurekAlert!, Asia Research News, Phys.org, Nanowerk, chemeurope.com, SCIENMAG, True Viral News, Mirage News

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日本語記事など

    1. 低酸素条件下で形成する代謝酵素集合体の観察
      三浦夏子
      実験医学別冊「フロントランナー直伝 相分離解析プロトコール」, 135–145.

    2. 1分子FRETと2-color二次元蛍光寿命相関分光法による核酸のマイクロ秒構造変化ダイナミクスの検出
      田中優仁, 許岩
      ぶんせき, 2022, 7, 261.

    3. 生体内の代謝を知る・みる・使う
      三浦夏子
      生物工学, 2022, 100, 5, 240–245.

    4. 研究室だより:大阪公立大学 大学院工学研究科化学工学分野 ナノ化学システム工学グループ(許研究室)
      許岩
      電気学会論文誌E, 2022, 142, 5, NL5_2.

    5. 固体NMRによる膜結合ペプチドの構造解析
      川村出
      Peptide Newsletter Japan, 2022, 124, 8–11.

    6. 人工細胞を創るという研究分野について
      松浦友亮
      細胞, 2022, 54, 4, 176–177.
      松浦領域代表が、月刊「細胞」2022年4月号の特集「要素から構築する人工細胞とその応用」を監修しました

    7. ホップ蔓由来セルロースナノファイバーの製造
      金井典子, 川村出
      JETI, 2022, 70, 4, 43–45.

    8. 細菌接着タンパク質と微生物固定化への利用
      堀克敏
      バイオインダストリー, 2022, 39, 3, 11–18.

    9. 動植物が電力源になる:バイオ発電技術
      高井まどか, 吉野正洋, 佐藤崇裕
      アグリバイオ, 2022, 6, 3, 218–223.

    10. 自己組織化ペプチドを用いたバイオ機能超分子材料の創製
      若林里衣, 神谷典穂, 後藤雅宏
      酵素工学ニュース, 2022, 86, 17–24.

    11. 量子カスケードレーザーを利用した振動円偏光二色性分光光度計の開発
      渡辺敬祐, 清水優, 小勝負純, 吉田純, 川村出, 佐藤久子
      JASCO Report, 2021, 63, 2, 43–48

    12. “低酸素条件下で形成する代謝酵素集合体の観察”
      三浦夏子
      実験医学別冊「フロントランナー直伝 相分離解析プロトコール」, 135–145.
      https://www.yodosha.co.jp/yodobook/book/9784758122597/

    13. “1分子FRETと2-color二次元蛍光寿命相関分光法による核酸のマイクロ秒構造変化ダイナミクスの検出”
      田中優仁, 許岩
      ぶんせき, 2022, 7, 261.
      https://bunseki.jsac.jp/archives/2646

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    受賞

    1. 2021.11.18
      許岩, 大阪府立大学工学研究科学術奨励賞

    2. 2022.04.01
      許岩, CREST細胞外微粒子 Young Innovator Award
      受賞タイトル:aifAを用いた高精度1分子観察に基づくエクソソームの不均一性解明の技術基盤の構築

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    その他(実用化・特許など)

    1. 2022.07.14
      A01班 築地グループ
      タンパク質の細胞膜局在誘導試薬「SLIPT-PM」販売開始(フナコシ株式会社)
      https://www.funakoshi.co.jp/contents/70609
      https://www.funakoshi.co.jp/contents/70604

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    プレスリリース・メディア報道など

    川野グループ:JACS Au論文関連

    プレスリリース

    ナノポアを用いた血中がんマーカーのパターン識別に成功!―DNAコンピューティング技術による並列計算を利用―, TUAT
    https://www.tuat.ac.jp/outline/disclosure/pressrelease/2022/20220627_01.html

    メディア報道
    1. 東京農工大、ナノポアを用いた血中がんマーカーのパターン識別に成功
      Nikkei Net,, 27 Jun 2022.

    2. Detection of cancer biomarkers from blood samples using nanopore-based DNA computing technology
      EurekAlert!, 27 Jun 2022.

    3. Detection of cancer biomarkers from blood samples using nanopore-based DNA computing technology
      Bioengineer.org, 27 Jun 2022.

    4. Detection of cancer biomarkers from blood samples using nanopore-based DNA computing technology
      ScienMag, 27 Jun 2022.

    5. 農工大、DNAコンピューティングとナノポア計測で胆管がんの識別に成功,
      TECH+, 28 Jun 2022.

    6. Nanopore Technology Detects Cancer Biomarkers from Patients’ Blood
      GEN, 28, Jun 2022.

    7. Detection of cancer biomarkers from blood samples using nanopore-based DNA computing technology
      ecancer, 28 Jun 2022.

    8. Nuevo método para detectar biomarcadores de cáncer con muestras de sangre
      Jano,, 29 Jun 2022.

    9. 利用纳米孔DNA技术从血液样本中检测癌症生物标志物
      ebiotrade,, 29 Jun 2022

    10. Cancer Biomarkers are detected from patients’ blood using nanopore technology
      list23, 29 Jun 2022.

    11. Nanopore Technology Detects Cancer Biomarkers from Patients’ Blood
      tetracyclined7k, 29 Jun 2022.

    12. Researchers use nanopore-based DNA computing technology to detect cancer
      AZO Life Sciences,1 Jul 2022.

    許グループ:J Mater Chem B論文関連

    研究論文A biomimetic anti-biofouling coating in nanofluidic channelsがJournal of Materials Chemistry B誌にHOT Paperに選ばれた, 2022年1月20日

    許グループ:Nano Lett論文関連

    ナノ流体デバイスによるナノスケールの超微小気液界面の作製に関する研究成果がNano Letters誌(2021年21巻24号)の表紙を飾った, 2021年12月22日

    プレスリリース

    「ナノスケールで物質の濃縮効果を発見―ナノ流体デバイスによる超微小気液界面の作製と効果―」、大阪府立大学とJSTより共同プレスリリース(2021年10月14日)

    メディア報道
    1. ナノスケールの超微小気液界面 大阪府大、高精度・均一に作製成功
      日刊工業新聞, 日刊電子版、2021年10月15日

    2. First controllable nanoscale gas-liquid interface fabricated
      EurekAlert!, 2021年10月19日

    3. First controllable nanoscale gas-liquid interface fabricated
      Asia Research News, 2021年10月19日

    4. First controllable nanoscale gas-liquid interface fabricated
      Phys.orgPhys.org, 2021年10月19日

    5. First controllable nanoscale gas-liquid interface fabricated
      Nanowerk, 2021年10月19日

    6. First controllable nanoscale gas-liquid interface fabricated
      Chem Europe, 2021年10月21日

    7. First controllable nanoscale gas-liquid interface fabricated
      ScienMag, 2021年10月19日

    8. First controllable nanoscale gas-liquid interface fabricated
      True Viral News, 2021年10月19日

    9. First controllable nanoscale gas-liquid interface fabricated
      Mirage News, 2021年10月20日

    10. NANO Letters Twitter
      @NanoLetters, 2021年11月6日

    11. 大阪府立大学许岩课题组Nano Letters:纳米级可控气液界面
      化学与材料科学, 2021年11月22日

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    国際学会発表

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    国内学会発表

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